Product Category:Pharmaceutical raw materials and intermediates
Grade :Pharmaceutical Grade
Appearance:White or Almost White Crystalline Powder
Usage:Exemestane is an irreversible, steroidal aromatase inactivator,structurally related to the natural substrate androstenedione.It acts as a false substrate for the aromatase enzyme,and is processed to an intermediate that binds irreversibly to the active site of the enzyme causing its inactivation,an effect also known as "suicide inhibition."By being structurally similar to enzyme targets.Exemestane can permanently binds to the enzymes,and prevent them from converting androgen into estrogen.
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